IK-930CAS号： 2563892-44-2分子式： C19H19F3N4O2S分子量： 424.44描述纯度储存/保存方法可溶性/溶解性靶点In vitro(体外研究)In vivo(体内研究)
| 产品描述 | |
| 描述 |
IK-930 is an orally active TEAD inhibitor (EC50 < 0.1 µM) with potent potency.
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| 纯度 |
98%
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| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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| 基本信息 | |
| 可溶性/溶解性 |
DMSO:90.0 mg/mL (212.0 mM)
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| 生物活性 | |
| 靶点 |
TEAD:<0.1 µM(EC50)
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| In vitro(体外研究) |
IK-930 (0-1 μM) is a potent and selective TEAD inhibitor.[2]
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| In vivo(体内研究) |
IK-930 (compound I-32) (10 mg/kg; p.o.) exhibits favorable pharmacokinetic parameters in BALB/c mice with Cmax of 1088 ng/mL and AUC 0-last of 4581 ng*h /mL.[1]
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