GW 1929 CAS号： 196808-24-9分子式： C30H29N3O4 分子量： 495.6描述应用纯度储存/保存方法形态密度熔点沸点折射率IC50PK值Ki 数据可溶性/溶解性
| 产品描述 | |
| 描述 |
GW 1929 is a potent, tyrosine-based PPARγ (peroxisome proliferator-activated receptor γ) agonist (EC50 = 13 nM for murine receptor and 6.2 nM for human receptor in cell-based transactivation assays).
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| 应用 |
A potent, tyrosine-based PPARγ
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| 纯度 |
>97%
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| 储存/保存方法 |
Store at -20° C
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| 形态 |
Solid
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| 基本信息 | |
| 密度 |
1.27 g/cm3 (Predicted)
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| 熔点 |
286° C (Predicted)
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| 沸点 |
749.18° C at 760 mmHg (Predicted)
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| 折射率 |
n20D 1.66 (Predicted)
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| IC50 |
PPARγ: IC50 = 6.2 nM (human); PPARγ: IC50 = 13 nM (mouse)
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| PK值 |
pKa: 3.91 (Predicted), pKb: 6.51 (Predicted)
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| Ki 数据 |
DOR: Ki= 1.13 µM (human); Progesterone receptor: Ki= 3.99 µM (bovine); NK-2R: Ki= 4.84 µM (human); CysLT1 Receptor: Ki= 5.46 µM (human); Adenosine A3-R: Ki= 8.09 µM (humaƱᩄ
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| 可溶性/溶解性 |
Soluble in DMSO (100 mg/ml), and methanol.
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