O-1918CAS号： 536697-79-7分子式： C19H26O2分子量： 286.41描述应用纯度储存/保存方法别名外观沸点折射率光学活性可溶性/溶解性MDLPubChem CID
| 产品描述 | |
| 描述 |
O-1918 is an analog of cannabidiol acting as a selective antagonist at the endothelial non-CB1/CB2 cannabinoid receptor. O-1918 induces endothelium-dependent vasodilation via a CB1/CB2/nitric oxide-independent mechanism. O-1918 blocks the abnormal cannabidiol-induced activation of the PI3-kinase/Akt pathway in vein endothelial cells. O-1918 is an inhibitor of GPR18. |
| 应用 |
A cannabidiol analog and antagonist at the endothelial cannabinoid receptor
|
| 纯度 |
≥95%
|
| 储存/保存方法 |
Store at -20° C，1 year.
|
| 基本信息 | |
| 别名 |
O1918；1,3-dimethoxy-5-methyl-2-[(1R,6R)-3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-benzene
|
| 外观 |
solution in methyl acetate
|
| 沸点 |
383.9° C at 760 mmHg (Predicted)
|
| 折射率 |
n20D 1.52 (Predicted)
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| 光学活性 |
α20/D -147°, c = 1 in ethanol
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| 可溶性/溶解性 |
Soluble in ethanol (~30 mg/ml), DMSO (~30 mg/ml), DMF (~30 mg/ml), and 1:1 solution of ethanol:PBS (pH 7.2) (0.5 mg/ml).
|
| MDL |
MFCD08062137
|
| PubChem CID |
40469923
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分子结构图
