RS 102895 HydrochlorideCAS号： 300815-41-2分子式： C21H21F3N2O2 HCl分子量： 426.86描述应用纯度储存/保存方法形态沸点折射率可溶性/溶解性MDLPubChem CID
| 产品描述 | |
| 描述 |
RS 102895 Hydrochloride is a CKR-2B (CCR2)-selective chemokine receptor antagonist (IC50 values are 0.36 and 17.8 μM for inhibition of human recombinant CKR-2B and CKR-1 (CCR2b and CCR1 receptors) respectively). Blocks MCP-1-stimulated calcium influx and chemotaxis with IC50 values of 32 nM and 1.7 μM respectively. Inhibits α1A-AR, α1D-AR and SR-1A (α1A, α1D and 5-HT1A receptors).
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| 应用 |
A CCR2-selective chemokine receptor antagonist
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| 纯度 |
>99%
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| 储存/保存方法 |
Desiccate at room temperature
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| 形态 |
Solid
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| 基本信息 | |
| 沸点 |
472.7° C at 760 mmHg (Predicted)
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| 折射率 |
n20D ~1.59 (Predicted)
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| 可溶性/溶解性 |
Soluble in DMSO (75 mM).
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| MDL |
MFCD08703093
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| PubChem CID |
16759153
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