AZD8931 diFuMaric AcidCAS号： 1196531-39-1分子式： C31H33ClFN5O11分子量： 706.1描述纯度储存/保存方法可溶性/溶解性靶点In vivo(体内研究)
| 产品描述 | |
| 描述 |
AZD8931 is a reversible and ATP competitive inhibitor of EGFR, ErbB2 and ErbB3 (IC50 of 4 nM, 3 nM and 4 nM, respectively).
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| 纯度 |
98%
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| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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| 基本信息 | |
| 可溶性/溶解性 |
DMSO:30 mg/mL (42.49 mM)
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| 生物活性 | |
| 靶点 |
ErbB3:4 nM, ErbB2:3 nM, EGFR:4 nM
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| In vivo(体内研究) |
AZD8931 significantly suppressed cell growth of IBC cells and induced apoptosis of human IBC cells in vitro.AZD8931 monotherapy inhibited xenograft growth[1].
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