NBQX CAS号： 118876-58-7分子式： C12H8N4O6S分子量： 336.28描述纯度储存/保存方法别名外观可溶性/溶解性靶点In vitro(体外研究)In vivo(体内研究)
| 产品描述 | |
| 描述 |
NBQX is a potent, selective and competitive AMPA receptor antagonist. |
| 纯度 |
98%
|
| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
|
| 基本信息 | |
| 别名 |
二羟基喹酮; FG9202
|
| 外观 |
yellow solid
|
| 可溶性/溶解性 |
DMSO : ≥ 75 mg/mL (223.03 mM)
|
| 生物活性 | |
| 靶点 |
AMPA receptor
|
| In vitro(体外研究) |
NBQX (FG9202) has a high affinity for AMPA and kainate binding sites with little or no affinity for the glutamate recognition site on the NMDA receptor complex.
|
| In vivo(体内研究) |
NBQX is neuroprotective in a focal ischaemia model in the rat when given as an i.v. bolus dose of 30 mg/kg at the time of MCA occlusion and again at 1 h post occlusion.
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分子结构图
