Mouse anti-LAP2 Monoclonal Antibody(1617CT859.9.32)描述别名宿主特异性反应种属应用分子量类型克隆号同种型储存/保存方法研究领域背景说明细胞定位UniProt参考文献
| 概述 | |
| 描述 |
Purified Mouse Monoclonal Antibody (Mab)
|
| 别名 |
LAP2抗体;Protein LAP2; Densin-180-like protein; Erbb2-interacting protein; Erbin; ERBB2IP; ERBIN; KIAA1225; LAP2
|
| 宿主 |
Mouse
|
| 特异性 |
This LAP2 antibody is generated from a mouse immunized with a recombinant protein of human LAP2.
|
| 反应种属 |
Human
|
| 应用 |
WB~~1:1000
|
| 分子量 |
Predicted molecular weight: 158kD
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
| 性能 | |
| 类型 |
Monoclonal Antibody
|
| 克隆号 |
1617CT859.9.32
|
| 同种型 |
IgG1,k
|
| 储存/保存方法 |
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
|
| 研究领域 |
Signal Transduction
|
| 靶标 | |
| 背景说明 |
Acts as an adapter for the receptor ERBB2, in epithelia. By binding the unphosphorylated ‘Tyr-1248’ of receptor ERBB2, it may contribute to stabilize this unphosphorylated state.
|
| 细胞定位 |
Cell junction, hemidesmosome Nucleus membrane. Note=Found in hemidesmosomes, which are cell-substrate adhesion complexes in stratified epithelia. In transfected cells, either diffusely distributed over the cytoplasm or concentrated at the basolateral membrane Colocalizes with the adrenergic receptors, ADREN1A and ADREN1B, at the nuclear membrane of cardiac myocytes (By similarity)
|
| UniProt |
Q96RT1
|
| 参考文献 | |
| 参考文献 |
Borg J.-P.,et al.Nat. Cell Biol. 2:407-414(2000).
Favre B.,et al.J. Biol. Chem. 276:32427-32436(2001). Nagase T.,et al.DNA Res. 6:337-345(1999). Nakajima D.,et al.DNA Res. 9:99-106(2002). Ota T.,et al.Nat. Genet. 36:40-45(2004). |
实验结果图
All lanes : Anti-LAP2 Antibody at 1:500-1:1000 dilution Lane 1: Hela whole cell lysate Lane 2: SW480 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 158 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
All lanes : Anti-LAP2 Antibody at 1:1000-1:2000 dilution Lane 1: Hela whole cell lysate Lane 2: HepG2 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 158 kDa Blocking/Dilution buffer: 5% NFDM/TBST.