VU 0238429CAS号： 1160247-92-6分子式： C17H12F3NO4分子量： 351.28描述纯度储存/保存方法别名外观可溶性/溶解性靶点In vitro(体外研究)
| 产品描述 | |
| 描述 |
A selective positive allosteric modulator of M5 receptors (EC50 values are 1.16, >30 and >30 μM at M5, M1 and M3 receptors respectively). Displays no activity at M2 and M4 receptors.
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| 纯度 |
98%
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| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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| 基本信息 | |
| 别名 |
1-(4-Methoxybenzyl)-5-trifluoroMethoxyisatin
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| 外观 |
powder
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| 可溶性/溶解性 |
DMSO : ≥ 150 mg/mL (427.01 mM)
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| 生物活性 | |
| 靶点 |
mAChR5
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| In vitro(体外研究) |
VU 0238429 is positive allosteric modulator of mAChR5 (M5), with an EC50 of 1.16 μM, >30-fold selectivity versus M1 and M3, with no M2 or M4 potentiator activity.
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分子结构图
