RS 8359

RS 8359CAS号: 105365-76-2分子式: C14H12N4O分子量: 252.27描述纯度储存/保存方法可溶性/溶解性In vivo(体内研究)

产品描述
描述
RS 8359 is a reversible inhibitor of monoamine oxidase A (MAO-A) with a selectivity ratio of about 2200 for the A:B enzyme types. RS 8359 has antidepressant activity.
纯度
96%
储存/保存方法
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
基本信息
可溶性/溶解性
DMSO:48 mg/mL (190.27 mM)
生物活性
In vivo(体内研究)
RS 8359 shows relatively little effect upon blood pressure when administered together with tyramine, thus effectively eliminating the ‘cheese’ effect which has contributed to the limited clinical use of the classical monoamine oxidase inhibitors. RS 8359 shows little affinity for the common central nervous system receptors and little anticholinergic effect[1].