AZD8309CAS号： 333742-48-6分子式： C15H14F2N4O2S2分子量： 384.42描述纯度储存/保存方法可溶性/溶解性In vivo(体内研究)
| 产品描述 | |
| 描述 |
AZD8309 is a potent, orally available antagonist of the chemokine receptor CXCR2 that regulates neutrophil transport, significantly reduces MPO in the pancreas and lung, and decreases trypsin and elastase activity in the pancreas.AZD8309 can be used to study a range of inflammatory diseases.
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| 纯度 |
98%
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| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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| 基本信息 | |
| 可溶性/溶解性 |
DMSO:45.0 mg/mL (117.1 mM)
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| 生物活性 | |
| In vivo(体内研究) |
Oral dministration of AZD8309 (50 mg/kg) reduced neutrophil migration and pancreatic protease activation in experimental pancreatitis in mice.[1]
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