CGP 7930CAS号： 57717-80-3分子式： C19H32O2分子量： 292.46描述应用储存/保存方法形态密度熔点沸点折射率IC50PK值可溶性/溶解性MDLPubChem CID
| 产品描述 | |
| 描述 |
CGP 7930 is a positive allosteric modulator of GABAB receptors. CGP 7930 increases the potency and efficacy of GABA at both native and recombinant GABAB receptors (EC50 values are 5.37 and 4.60μM respectively) and enhances the inhibitory effect of the agonist L-baclofen in cultured cortical neurons.
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| 应用 |
Positive allosteric modulator of GABAB receptors
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| 储存/保存方法 |
Desiccate at room temperature
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| 形态 |
Solid
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| 基本信息 | |
| 密度 |
~1.0 g/cm3 (Predicted)
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| 熔点 |
139.37° C (Predicted)
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| 沸点 |
~364.7° C at 760 mmHg (Predicted)
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| 折射率 |
n20D 1.51 (Predicted)
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| IC50 |
Plasmodium falciparum: IC50 = 15.85 µM
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| PK值 |
pKa: 12.55 (Predicted)
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| 可溶性/溶解性 |
Soluble in ethanol (100 mM), and DMSO (100 mM).
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| MDL |
MFCD04040028
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| PubChem CID |
5024764
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