MB-07811CAS号： 852948-13-1分子式： C28H32ClO5P分子量： 514.98描述纯度储存/保存方法In vitro(体外研究)In vivo(体内研究)
| 产品描述 | |
| 描述 |
MB-07811 is an orally active HepDirect prodrug of MB07344 with cholesterol and triglycerides lowering activity. MB-07811 is an agonist of liver-targeted THR-β.
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| 纯度 |
97%
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| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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| 生物活性 | |
| In vitro(体外研究) |
MB-07811 has a low affinity for thyroid hormone receptors with a Ki of 14.6 μM for TRβ and a Ki of 12.5 μM for TRα[2].
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| In vivo(体内研究) |
In diet-induced obese mice, MB-07811 (0.3-30 mg/kg) decreases cholesterol and triglycerides[2].
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