Ro 5212773CAS号： 1110781-88-8分子式： C20H21F3N2O2分子量： 378.39描述纯度储存/保存方法可溶性/溶解性靶点In vivo(体内研究)
| 产品描述 | |
| 描述 |
Ro 5212773 (Epptb) is a selective TAAR1 antagonist.
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| 纯度 |
98%
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| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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| 基本信息 | |
| 可溶性/溶解性 |
DMSO:55 mg/ml (145.35 mM)
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| 生物活性 | |
| 靶点 |
TAAR1:28 nM
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| In vivo(体内研究) |
EPPTB prevents the reduction of the firing frequency of DA neurons induced by p-tyramine (p-tyr), a nonselective TAAR1 agonist. the EPPTB effects were JPent in Taar1 knockout mice, ruling out off-target effects[2].
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