BRD 9757CAS号： 1423058-85-8分子式： C6H9NO2分子量： 127.14描述纯度储存/保存方法可溶性/溶解性In vitro(体外研究)
| 产品描述 | |
| 描述 |
BRD 9757 is a selective inhibitor of HDAC6 (IC50 = 30 nM).
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| 纯度 |
98%
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| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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| 基本信息 | |
| 可溶性/溶解性 |
DMSO:<1.27 mg/mL (10 mM)
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| 生物活性 | |
| In vitro(体外研究) |
The IC50s are 0.638 μM, 1.79 μM, 0.694 μM, 21.80 μM, 18.32 μM, 12.61 μM, 1.09 μM and >33.33 μM, respectively for HDAC1, HDAC2, HDAC3, HDAC4, HDAC5, HDAC7, HDAC8 and HDAC9. BRD 9757 (10-30 μM) selectively increases Ac-tubulin levels without affecting histone acetylation[1].
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