MK-0752CAS号： 471905-41-6分子式： C21H21ClF2O4S分子量： 442.9描述纯度储存/保存方法可溶性/溶解性靶点参考文献
| 产品描述 | |
| 描述 |
MK-0752 is a moderately potent γ-secretase inhibitor, which reduces Aβ40 production with IC50 of 5 nM. Phase 1/2. |
| 纯度 |
99%
|
| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
|
| 基本信息 | |
| 可溶性/溶解性 |
Ethanol：45mg/mL(101.6mM)
DMSO：89mg/ml(200.95 mM) |
| 生物活性 | |
| 靶点 |
(gamma)-secretase
|
| 参考文献 | |
| 参考文献 |
[1] Cook JJ, et al. J Neurosci, 2010, 30(19), 6743-6750. [2] Harrison H, et al. Cancer Res, 2010, 70(2), 709-718. |
分子结构图
