PF 750 is an irreversible fatty acid amide hydrolase (FAAH) inhibitor (IC₅₀ = 16.2 nM) that displays no activity at a range of other serine hydrolases. Orally active and selectively inhibits FAAH within the central nervous system.

An irreversible inhibitor of FAAH

>98%

Store at -20° C

Solid

~1.2 g/cm³ (Predicted)

225.43° C (Predicted)

~582.7° C at 760 mmHg (Predicted)

n²⁰_D 1.67 (Predicted)

FAAH: IC₅₀ = 15.85 nM (human)

pK_b: 5.09 (Predicted)

Soluble in DMSO (100 mM), ethanol (100 mM), DMF (~20 mg/ml), and 1:5 solution of DMSO:PBS (pH 7.2) (~0.13 mg/ml).

MFCD10567109

25154868