XCT790CAS号： 725247-18-7分子式： C23H13F9N4O3S分子量： 596.42描述纯度储存/保存方法别名外观可溶性/溶解性靶点参考文献
| 产品描述 | |
| 描述 |
XCT-790是雌激素相关受体（ERR）α反向激动剂，能诱导化疗抗性的癌细胞死亡。 |
| 纯度 |
＞98%
|
| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
|
| 基本信息 | |
| 别名 |
XCT 790; XCT-790
|
| 外观 |
yellow powder
|
| 可溶性/溶解性 |
DMSO : 21 mg/mL (35.21 mM; Need ultrasonic and warming)
|
| 生物活性 | |
| 靶点 |
Estrogen Receptor_ERR
|
| 参考文献 | |
| 参考文献 |
[1]. Wu F, et al. Estrogen-related receptor alpha (ERRalpha) inverse agonist XCT-790 induces cell death in chemotherapeutic resistant cancer cells. Chem Biol Interact. 2009 Oct 7;181(2):236-42.
[2]. Busch BB, et al. Identification of a selective inverse agonist for the orphan nuclear receptor estrogen-related receptor alpha. J Med Chem. 2004 Nov 4;47(23):5593-6. |
分子结构图
