SNX0723

SNX0723CAS号: 1073969-18-2分子式: C22H26FN3O3分子量: 399.46描述纯度储存/保存方法可溶性/溶解性In vitro(体外研究)

产品描述
描述
SNX0723 is a potent Hsp90 Inhibitor with anti-Plasmodium activity. SNX0723 shows high binding affinity for HsHsp90 and PfHsp90 with Kis of 4.4 and 47 nM, respectively. SNX0723 inhibits liver-stage P. berghei ANKA parasites with the EC50 of 3.3 μM.
纯度
98%
储存/保存方法
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
基本信息
可溶性/溶解性
DMSO:18.9mg/mL (47.3mM)
生物活性
In vitro(体外研究)
SNX0723 inhibits P. falciparum Dd2 blood-stage parasites and P. berghei ANKA liver-stage parasites, EC50 are 7.4μM and 6.5μM, respectively[1].