GW 766994CAS号： 408303-43-5分子式： C21H24Cl2N4O3分子量： 451.35描述纯度储存/保存方法别名可溶性/溶解性In vitro(体外研究)
| 产品描述 | |
| 描述 |
GW 766994 is a specific and oral chemokine receptor-3 (CCR3) antagonist, which has entered clinical trial for asthma and eosinophilic bronchitis.
|
| 纯度 |
98%
|
| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
|
| 基本信息 | |
| 别名 |
GW 994
|
| 可溶性/溶解性 |
DMSO : 56 mg/mL (124.07 mM; Need ultrasonic)
|
| 生物活性 | |
| In vitro(体外研究) |
GW 766994 is a specific chemokine receptor-3 (CCR3) antagonist, which has entered clinical trial for asthma and eosinophilic bronchitis. GW 766994 (10 μM) reverses CCL11-induced activation of CDK5, phosphorylations of CDK5, GSK3β, and increased phosphorylation of tau in hippocampal neurons.
|
分子结构图
