A 286982CAS号： 280749-17-9分子式： C24H27N3O4S分子量： 453.55描述应用储存/保存方法形态别名密度熔点沸点折射率IC50可溶性/溶解性
| 产品描述 | |
| 描述 |
A 286982 is a potent inhibitor of the LFA-1/ICAM-1 interaction (IC50 = 44 and 35 nM in LFA-1/ICAM-1 binding and LFA-1-mediated cell adhesion, respectively).
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| 应用 |
A potent LFA-1/ICAM-1 interaction inhibitor
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| 储存/保存方法 |
Store at -20° C
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| 形态 |
Solid
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| 基本信息 | |
| 别名 |
(2E)-1-(4-Acetyl-1-piperazinyl)-3-[4-[[2-(1-methylethyl)phenyl]thio]-3-nitrophenyl]-2-propen-1-one
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| 密度 |
~1.3 g/cm3 (Predicted)
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| 熔点 |
265.50° C (Predicted)
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| 沸点 |
~648.8° C at 760 mmHg (Predicted)
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| 折射率 |
n20D 1.64 (Predicted)
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| IC50 |
LFA-1-mediated cell adhesion assays: IC50 = 35 nM; LFA-1/ICAM-1 binding: IC50 = 44 nM
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| 可溶性/溶解性 |
Soluble in DMSO (100 mM), and ethanol (50 mM).
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