Rabbit anti-SP1 Polyclonal Antibody(C-term P692)别名宿主特异性反应种属预测反应种属应用分子量类型同种型储存/保存方法背景说明参考文献
| 概述 | |
| 别名 |
SP1抗体;Transcription factor Sp1; SP1; TSFP1
|
| 宿主 |
Rabbit
|
| 特异性 |
This SP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 677-707 amino acids from the C-terminal region of human SP1.
|
| 反应种属 |
Human
|
| 预测反应种属 |
mouse, Rat
|
| 应用 |
WB, IHC-P, FC, IF
|
| 分子量 |
Predicted molecular weight: 81kD
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
| 性能 | |
| 类型 |
Polyclonal Antibody
|
| 同种型 |
Rabbit Ig
|
| 储存/保存方法 |
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
|
| 靶标 | |
| 背景说明 |
Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression.
|
| 参考文献 | |
| 参考文献 |
Pan, Q., et al. Biochem. Biophys. Res. Commun. 401(2):306-312(2010)
Mucha, M., et al. J. Neurosci. 30(40):13235-13245(2010) Imanishi, M., et al. Biochem. Biophys. Res. Commun. 400(4):625-630(2010) Jutooru, I., et al. J. Biol. Chem. 285(33):25332-25344(201皪Ỵ皫 㟹皩腙癹 皢䭨༯鏰2 ༯ð 㺣癷 ` 帉癷 |