LY3372689 is an orally active O-GlcNAcase (OGA) enzyme inhibitor for tau protein-based disorders including Alzheimer’s disease.

98%

Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.

DMSO:225.0 mg/mL (586.8 mM)

In rat studies, LY3372689 demonstrated a dose-dependent change in OGA EO following a single oral dose with a maximum EO of greater than 90%. A plasma concentration-dependent increase in brain OGA EO was observed with EO exceeding 90% at 24 hours following the highest dose of LY3372689 administered.[1]