LJH685CAS号： 1627710-50-2分子式： C22H21F2N3O分子量： 381.42描述纯度储存/保存方法别名外观可溶性/溶解性靶点In vitro(体外研究)
| 产品描述 | |
| 描述 |
LJH685 is a selective and potent RSK inhibitor. |
| 纯度 |
98%
|
| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
|
| 基本信息 | |
| 别名 |
LJH-685,LJH 685
|
| 外观 |
Powder
|
| 可溶性/溶解性 |
Ethanol :16 mg/mL (41.9 mM)
DMSO :71 mg/mL (186.1 mM) |
| 生物活性 | |
| 靶点 |
RSK3 ,RSK2 ,RSK1
|
| In vitro(体外研究) |
LJH685 modulates YB1 phosphorylation by potently and selectively inhibiting RSK in cells. In MAPK pathway–dependent cancer cell lines, LJH685 shows antiproliferative effects, and causes cell-cycle regulation and apoptosis induction.
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分子结构图
