PD 168368CAS号： 204066-82-0分子式： C31H34N6O4分子量： 554.65描述应用纯度储存/保存方法外观密度沸点折射率PK值Ki 数据可溶性/溶解性MDLPubChem CID
| 产品描述 | |
| 描述 |
PD 168368 is a NMBR (Neuromedin B) antagonist displaying ~40-fold selectivity over GRP-R, BB2 and >300-fold selectivity over BRS-R. Antagonizes neuromedin B-stimulated Ca2+ release and inhibits proliferation of rat glioma cells. |
| 应用 |
A NMBR (Neuromedin B) antagonist
|
| 纯度 |
≥96%
|
| 储存/保存方法 |
Store at -20℃
|
| 基本信息 | |
| 外观 |
Pale yellow solid
|
| 密度 |
~1.3 g/cm3 (Predicted)
|
| 沸点 |
~819.7° C at 760 mmHg (Predicted)
|
| 折射率 |
n20D 1.66 (Predicted)
|
| PK值 |
pKa: 11.6 (Predicted), pKb: 5.65 (Predicted)
|
| Ki 数据 |
NMBR: Ki= 0.15 nM (human); GRPR: Ki= 17 nM (human)
|
| 可溶性/溶解性 |
Soluble in water (700 mg/L at 25 °C), chloroform (44.51 g/100mL at 25 °C), dichloromethane (19.20 g/100mL at 25 °C), methanol (9.98 g/100mL at 25 °C), DMSO (50 mM), ethanol (1.28 g/100mL at 25 °C)
|
| MDL |
MFCD09971100
|
| PubChem CID |
9937534
|
分子结构图
