Tiotropium bromide

Tiotropium bromideCAS号: 136310-93-5分子式: C19H22BrNO4S2分子量: 472.42描述纯度储存/保存方法别名外观可溶性/溶解性靶点参考文献

产品描述
描述

Tiotropium is a long-acting, 24 hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD). Tiotropium is a muscarinic receptor antagonist, on topical application it acts mainly on M3 muscarinic receptors located in the airways to produce smooth muscle relaxation, thus producing a bronchodilatory effect.

纯度
>98%
储存/保存方法
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
基本信息
别名
噻托溴铵;BA679 BR
外观
白色或类白色结晶性粉末
可溶性/溶解性
DMSO : ≥ 30 mg/mL (63.50 mM)
生物活性
靶点
mAChR
参考文献
参考文献
  • 1. Hansel TT, Barnes PJ. Drugs Today (Barc). 2002 Sep;38(9):585-600.
  • 2. Barnes PJ, et al. Life Sci. 1995;56(11-12):853-9.
  • 分子结构图

    Tiotropium bromide