BI-671800CAS号： 1093108-50-9分子式： C25H26F3N5O3分子量： 501.50描述纯度储存/保存方法别名可溶性/溶解性In vitro(体外研究)In vivo(体内研究)
| 产品描述 | |
| 描述 |
BI-671800 is a highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2), with IC50 values of 4.5 nM and 3.7 nM for PGD2 binding to CRTH2 in hCRTH2 and mCRTH2 transfected cells, respectively. BI-671800 has potential for the treatment of poorly controlled asthma.
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| 纯度 |
98%
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| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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| 基本信息 | |
| 别名 |
AP-761
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| 可溶性/溶解性 |
DMSO : 135 mg/mL (269.19 mM; Need ultrasonic)
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| 生物活性 | |
| In vitro(体外研究) |
BI-671800 (compound A) exhibits low nM potency as an antagonist of human or mouse CRTH2 in transfected cells.
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| In vivo(体内研究) |
BI-671800 (compound A) exhibits low nM potency as an antagonist of human or mouse CRTH2 in transfected cells.
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分子结构图
