PDGFR/VEGFR2 Tyrosine Kinase Inhibitor, 5-Br SU6668CAS号： 251356-32-8分子式： C18H17BrN2O3分子量： 389.2描述应用储存/保存方法形态别名可溶性/溶解性PubChem CID
| 产品描述 | |
| 描述 |
PDGFR/VEGFR2 Tyrosine Kinase Inhibitor, 5-Br SU6668 is a cell-permeable, ATP-binding pocket-targeting, 5-bromoindolinone analog of SU6668. PDGFR/VEGFR2 Tyrosine Kinase Inhibitor, 5-Br SU6668 is equally potent as SU6668 in inhibiting PDGFR, while increasing activity against VEGFR2 and FGFR1 in cell-free kinase assays. Inhibits cell proliferation mediated by VEGF, FGF, and PDGFβ. Little effect against EGF-mediated cell proliferation or EGFR in vitro kinase activity.
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| 应用 |
A potent PDGFR, VEGFR2, and FGFR1 inhibitor
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| 储存/保存方法 |
Store at 4° C
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| 形态 |
Solid
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| 基本信息 | |
| 别名 |
(Z)-3-(2,4-Dimethyl-5-(2-oxo-1,2-dihydro-indol-3-ylidenemethyl-5-bromo)-1H-pyrrol-3-yl)-propionic acid
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| 可溶性/溶解性 |
Soluble in DMSO
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| PubChem CID |
53735577
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