GYKI 53655 hydrochlorideCAS号： 143692-48-2分子式： C19H20N4O3•HCl分子量： 388.85描述应用储存/保存方法形态别名IC50可溶性/溶解性MDLPubChem CID
| 产品描述 | |
| 描述 |
GYKI 53655 hydrochloride is a non-competitive AMPA and kainate receptor antagonist. This compound has also been shown to block GluK3 homomeric receptors (IC50 = 63 µM) and GluK2b(R)/GluK3 heteroreceptors at high concentrations. AMPA is a transmembrane glutamate receptor composed of the subunits GluR-1,2,3,4. |
| 应用 |
A non-competitive AMPA and kainate receptor antagonist
|
| 储存/保存方法 |
Desiccate at room temperature
|
| 形态 |
Solid
|
| 基本信息 | |
| 别名 |
1-(4-Aminophenyl)-3-methylcarbamyl-4-methyl-3,4-dihydro-7,8-methylenedioxy-5H-2,3-benzodiazepine hydrochloride
|
| IC50 |
GluK3 homomeric receptors: IC50 = 63 µM; GluK2b(R)/GluK3 heteroreceptors : IC50 = 32 µM
|
| 可溶性/溶解性 |
Soluble in water (100 mM), and DMSO (100 mM).
|
| MDL |
MFCD01941362
|
| PubChem CID |
126757
|
分子结构图
