XL-647

XL-647CAS号: 651031-01-5分子式: C24H25Cl2FN4O2分子量: 491.39描述应用储存/保存方法形态密度熔点沸点折射率可溶性/溶解性PubChem CID

产品描述
描述
XL657 is an extremely potent and selective inhibitor of EGFR phosphorylation (IC50 = 0.3 nM). Inhibition of EGFR blocks signal transduction and thus impedes vascularization. Also inhibits other receptor tyrosine kinases such as Neu (ErbB2), Flk-1 (KDR), EphB4, and Flt-4.
应用
A potent and selective EGFR phosphorylation inhibitor
储存/保存方法
Store at -20° C
形态
Solid
基本信息
密度
~1.4 g/cm3 (Predicted)
熔点
243.07° C (Predicted)
沸点
~567.9° C at 760 mmHg (Predicted)
折射率
n20D 1.63 (Predicted)
可溶性/溶解性
Soluble in DMSO.
PubChem CID
10458325