CP96345CAS号： 132746-60-2分子式： C28H32N2O分子量： 412.57描述应用纯度储存/保存方法形态外观密度熔点沸点折射率IC50PK值Ki 数据可溶性/溶解性MDLPubChem CID
| 产品描述 | |
| 描述 |
CP 96345 is a selective and potent non-peptide NK1 receptor antagonist. Attenuates substance P-induced salivary response and inhibits neurogenic inflammation.
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| 应用 |
A selective and potent non-peptide NK1receptor antagonist
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| 纯度 |
≥98%
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| 储存/保存方法 |
Store at room temperature
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| 形态 |
Solid
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| 基本信息 | |
| 外观 |
Powder
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| 密度 |
~1.2 g/cm3 (Predicted)
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| 熔点 |
219.07° C (Predicted)
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| 沸点 |
~541.5° C at 760 mmHg (Predicted)
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| 折射率 |
n20D 1.63 (Predicted)
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| IC50 |
NK-1R: IC50 = 0.2 nM (human); Neurokinin 1 receptor: IC50 = 0.4 nM (guinea pig); U373 MG: IC50 = 9 nM (human); Neurokinin 1 receptor: IC50 = 24 nM (mouse); Neurokinin 1 receptor: IC50 = 32 nM (rat)
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| PK值 |
pKb: 9.99 (Predicted)
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| Ki 数据 |
NK-1R: Ki= 0.4 nM (human); U11 MG: Ki= 4 nM (human)
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| 可溶性/溶解性 |
Soluble in DMSO (24 mg/ml).
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| MDL |
MFCD00900615
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| PubChem CID |
104943
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