AZD7624CAS号： 1095004-78-6分子式： C27H30FN5O3分子量： 491.56描述纯度储存/保存方法可溶性/溶解性靶点In vitro(体外研究)
| 产品描述 | |
| 描述 |
AZD7624 is an p38 inhibitor. It has potent anti-inflammatory activity.
|
| 纯度 |
98%
|
| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
|
| 基本信息 | |
| 可溶性/溶解性 |
DMSO:50 mg/mL (101.72 mM)
|
| 生物活性 | |
| 靶点 |
TNFα:8.4(human mononuclear cells), 8.1(whole blood), 9.0 (alveolar macrophages)
|
| In vitro(体外研究) |
AZD7624 inhibits LPS-induced TNFα in human mononuclear cells, in whole blood as well as in alveolar macrophages in vitro, with pIC50s of 8.4, 8.1, and 9.0[1]. AZD7624 is an inhaled p38 inhibitor, with potent anti-inflammatory activity.
|