A-71623 is a tetrapeptide that acts as a robust and selective CCK (cholecystokinin) receptor agonist. CCK is a neuroendocrine peptide described to play an important role in cell growth, cell proliferation, and other biological functions. Studies report that in comparison to other cholecystokinin agonists A-71623 does not have a tyrosine residue in which sulfation is necessary for strong cholecystokinin agonist activity in larger peptides. The compound has been used in animal studies to suppress appetite.

A potent CCK agonist with 1200-fold selectivity over the CCK2 receptor

Desiccate at -20° C

Solid

1.29 g/cm³ (Predicted)

1126.59° C at 760 mmHg (Predicted)

n²⁰_D 1.62 (Predicted)

CCK-AR: IC₅₀ = 3.7 nM

Soluble in 30% acetonitrile / 0.2% NH4OH (0.67 mg/ml ).

MFCD00897724

121964