BMS-986176CAS号: 1815613-42-3分子式: C19H23F4N3O分子量: 385.4描述储存/保存方法可溶性/溶解性靶点In vitro(体外研究)
产品描述 | |
描述 |
AAK1-IN-1 is a highly selective and potent inhibitor of adaptor associated kinase 1 (AAK1, IC50 = 2 nM).
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储存/保存方法 |
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
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基本信息 | |
可溶性/溶解性 |
DMSO:220 mg/mL (570.84 mM)
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生物活性 | |
靶点 |
AAK1:2.2 nM
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In vitro(体外研究) |
AAK1-IN-1can be used for neurodegenerative disease studies. Adaptor associated kinase 1 (AAK1) is a member of the Arkl/Prkl family of serine/threonine kinases and modulates clatherin coated endocytosis. and receptor-mediated endocytosis[1].
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