BMS-986176

BMS-986176CAS号: 1815613-42-3分子式: C19H23F4N3O分子量: 385.4描述储存/保存方法可溶性/溶解性靶点In vitro(体外研究)

产品描述
描述
AAK1-IN-1 is a highly selective and potent inhibitor of adaptor associated kinase 1 (AAK1, IC50 = 2 nM).
储存/保存方法
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
基本信息
可溶性/溶解性
DMSO:220 mg/mL (570.84 mM)
生物活性
靶点
AAK1:2.2 nM
In vitro(体外研究)
AAK1-IN-1can be used for neurodegenerative disease studies. Adaptor associated kinase 1 (AAK1) is a member of the Arkl/Prkl family of serine/threonine kinases and modulates clatherin coated endocytosis. and receptor-mediated endocytosis[1].