LYN-1604 diHydrochlorideCAS号: 2310109-38-5分子式: C33H45Cl4N3O2分子量: 657.54描述纯度储存/保存方法可溶性/溶解性靶点In vitro(体外研究)
产品描述 | |
描述 |
LYN-1604 is a novel ULK1 activator.It inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.
|
纯度 |
98%
|
储存/保存方法 |
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
|
基本信息 | |
可溶性/溶解性 |
DMSO:25 mg/mL (38.02 mM)
|
生物活性 | |
靶点 |
ULK1:18.94 nM (EC50)
|
In vitro(体外研究) |
LYN-1604, to be the best candidate for a ULK1 agonist.?LYN-1604 induced cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.?LYN-1604 has potential for good therapeutic effects on TNBC by targeting ULK1-modulated cell death in vivo
|