WAY-600

WAY-600CAS号: 1062159-35-6分子式: C28H30N8O 分子量: 494.59描述纯度储存/保存方法可溶性/溶解性参考文献

产品描述
描述
WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 nM; blocks mTORC1/P-S6K(T389) and mTORC2/P-AKT(S473) but not P-AKT(T308); selective for mTOR than PI3Kα (>100-fold) and PI3Kγ (>500-fold).
纯度
>98%
储存/保存方法
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
基本信息
可溶性/溶解性
体外:
DMSO 22mg/mL(44.48mM)
Ethanol 2mg/mL(4.04mM)
Water <1mg>
参考文献
参考文献

[1] Yu K, et al, Cancer Res, 2009, 69(15), 6232-6240.

分子结构图

WAY-600