AZD-7594CAS号： 1196509-60-0分子式： C32H32F2N4O6分子量： 606.62描述纯度储存/保存方法别名可溶性/溶解性In vitro(体外研究)In vivo(体内研究)
| 产品描述 | |
| 描述 |
AZD-7594 is a potent selective nonsteroidal glucocorticoid receptor modulator, with an IC50 of 0.9 nM.
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| 纯度 |
98%
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| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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| 基本信息 | |
| 别名 |
Velsecorat；AZ13189620；AZD7594
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| 可溶性/溶解性 |
DMSO : ≥ 83.3 mg/mL (137.32 mM)
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| 生物活性 | |
| In vitro(体外研究) |
AZD-7594 is a potent selective nonsteroidal glucocorticoid receptor modulator, with an IC50 of 0.9 nM. AZD-7594 shows no effect on progesterone receptor, mineralocorticoid receptor, Androgen receptor, ERα or ERβ (IC50, > 10 μM).
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| In vivo(体内研究) |
AZD-7594 has anti-inflammatory activity, and efficiently inhibits rat lung edema.
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