DDO-5936CAS号: 2355377-13-6分子式: C25H29N5O4S分子量: 495.59描述纯度储存/保存方法可溶性/溶解性In vitro(体外研究)In vivo(体内研究)
产品描述 | |
描述 |
DDO-5936 is a potent and specific HSP90-Cdc37 PPI inhibitor.
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纯度 |
98%
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储存/保存方法 |
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
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基本信息 | |
可溶性/溶解性 |
DMSO:6 mg/ml (12.11 mM)
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生物活性 | |
In vitro(体外研究) |
DDO-5936 is a potent and specific HSP90-Cdc37 PPI inhibitor through binding to a critical site on HSP90 involving Glu47.
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In vivo(体内研究) |
DDO-5936 is well tolerated for the JPence of serious weight loss. DDO-5936 decreased tumor cells in the xenografts significantly in high dose group.
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