DDO-5936

DDO-5936CAS号: 2355377-13-6分子式: C25H29N5O4S分子量: 495.59描述纯度储存/保存方法可溶性/溶解性In vitro(体外研究)In vivo(体内研究)

产品描述
描述
DDO-5936 is a potent and specific HSP90-Cdc37 PPI inhibitor.
纯度
98%
储存/保存方法
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
基本信息
可溶性/溶解性
DMSO:6 mg/ml (12.11 mM)
生物活性
In vitro(体外研究)
DDO-5936 is a potent and specific HSP90-Cdc37 PPI inhibitor through binding to a critical site on HSP90 involving Glu47.
In vivo(体内研究)
DDO-5936 is well tolerated for the JPence of serious weight loss. DDO-5936 decreased tumor cells in the xenografts significantly in high dose group.