VU6015929

VU6015929CAS号: 2442597-56-8分子式: C24H19F4N5O2分子量: 485.43描述纯度储存/保存方法可溶性/溶解性靶点In vitro(体外研究)

产品描述
描述
VU6015929 is an inhibitor of active dual discoidin domain receptor 1/2 (DDR1/2)( IC50s of 4.67 nM and 7.39 nM, respectively).
纯度
98%
储存/保存方法
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
基本信息
可溶性/溶解性
DMSO:250 mg/mL (515.01 mM)
生物活性
靶点
DDR2:7.39 nM, DDR1:4.67 nM
In vitro(体外研究)
VU6015929 potently blocks collagen-induced DDR1 activation and collagen-IV production, suggesting DDR1 inhibition as an exciting target for antifibrotic therapy[1].