RU 58841 is a specific androgen receptor antagonist or anti-androgen used as a topical treatment for acne, androgenetic alopecia and hirsutism. RU 58841 displays high affinity for the hamster prostate and flank organ (F.O.) androgen receptors. In vivo, when topically applied, it exerts a potent dose-dependent regression of F.O. area at a dose as low as 1 microgram/animal while being devoid of antiandrogenic activity on deep accessory sex organs and of any effect on testosterone level up to 100 micrograms/animal. RU 58841 has a dramatic effect on hair regrowth.

>98%

Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.

4-[3-(4-羟基丁基)-4,4-二甲基-2,5-二氧代-1-咪唑啉]-2-(三氟甲基)苯甲腈

10 mM in DMSO

RU 58841, a new specific topical antiandrogen: a candidate of choice for the treatment of acne, androgenetic alopecia and hirsutism.
Battmann T,et al. J Steroid Biochem Mol Biol. 1994 Jan;48(1):55-60. PMID:

分子结构图