RU 58668CAS号： 151555-47-4分子式： C34H43F5O5S分子量： 658.76描述应用纯度储存/保存方法形态别名折射率IC50PubChem CID
| 产品描述 | |
| 描述 |
RU 58668 is a pure antiestrogen that downregulates estrogen receptor expression (IC50 = 0.04 nM). Has been shown to display potent antiproliferative activity in vitro (IC50 = 0.035 – 0.09 nM in MCF-7 cells) and causes long term regression of tamoxifen resistant MCF-7
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| 应用 |
A pure antiestrogen
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| 纯度 |
≥95%
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| 储存/保存方法 |
Store at 4° C
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| 形态 |
Solid
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| 基本信息 | |
| 别名 |
(8S,9R,13S,14S,17S)-13-methyl-11-[4-[5-(4,4,5,5,5-pentafluoropentylsulfonyl)pentoxy]phenyl]-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol
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| 折射率 |
n20D 1.54
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| IC50 |
downregulates estrogen receptor expression: IC50 = 0.04 nM (MCF-7 cells); potent antiproliferative activity: IC50 = 0.035 – 0.09 nM (MCF-7 cells)
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| PubChem CID |
119604
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