MLS0315771CAS号： 727664-91-7分子式： C15H12FNOS分子量： 273.33描述纯度储存/保存方法可溶性/溶解性In vitro(体外研究)
| 产品描述 | |
| 描述 |
MLS0315771 is a potent and biologically active competitive phosphomannose isomerase (MPI) inhibitor, with an IC50 ~1 μM and a Ki of 1.4 μM.
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| 纯度 |
98%
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| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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| 基本信息 | |
| 可溶性/溶解性 |
DMSO : 100 mg/mL (365.86 mM; Need ultrasonic)
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| 生物活性 | |
| In vitro(体外研究) |
MLS0315771 increases mannose flux toward glycosylation.MLS0315771 toxicity at higher concentrations is an off-target effect. MLS0315771 is toxic to the zebrafish embryos above 2 μM. At 8-10 μM, ~50% embryos appeare sick within 20 min, and most of them die by 30-60 min.
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分子结构图
