NBD-556CAS号: 333353-44-9分子式: C17H24ClN3O2分子量: 337.84描述纯度储存/保存方法可溶性/溶解性In vitro(体外研究)
产品描述 | |
描述 |
NBD-556, a CD4 mimetic, is a potent HIV-1 entry inhibitor that blocks the gp120-CD4 interaction. NBD-556 shows potent cell fusion and virus-cell fusion inhibitory activity at low micromolar levels.
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纯度 |
98%
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储存/保存方法 |
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
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基本信息 | |
可溶性/溶解性 |
DMSO : 33.33 mg/mL (98.66 mM; Need ultrasonic)
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生物活性 | |
In vitro(体外研究) |
NBD-556 (1-100 μM) inhibits HIV-1 envelope-mediated virus-cell and cell-cell fusion.
NBD-556 inhibits the infection of MT-2 cells by laboratory-adapted HIV-1 IIIB, MN, and V32 strains, with IC50s of 6.5, 15.9, and 5.3 µM, respectively. |
分子结构图