AG 556CAS号： 133550-41-1分子式： C20H20N2O3分子量： 336.4描述纯度储存/保存方法形态别名外观IC50可溶性/溶解性
| 产品描述 | |
| 描述 |
AG 556 selectively inhibits epidermal growth factor receptor kinase autophosphorylation (IC50 = 5μM) over HER1/2 autophosphorylation. Also blocks LPS-induced TNF-α production. AG 556 is an inhibitor of EGFR. |
| 纯度 |
≥98%
|
| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
|
| 形态 |
Solid
|
| 基本信息 | |
| 别名 |
(E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(4-phenylbutyl)acrylamide
|
| 外观 |
Yellow solid.
|
| IC50 |
Glutamate NMDA receptor; Grin1/Grin2b: IC50 = 0.56 µM (rat); HER1-2 kinase: IC50 = 1.1 µM; Alpha-1a adrenergic receptor: IC50 = >100 µM (human); EGFR: IC50 = >500 µM
|
| 可溶性/溶解性 |
Soluble in DMSO, and DMF. Insoluble in water.
|
分子结构图
