OT-551 HCl is an NF-Κb inhibitor, a disubstituted hydroxylamine with antioxidant properties can be used for the treatment of cataracts and age-related macular degeneration and geographic atrophy (GA).

98%

Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.

DMSO:3.6 mg/mL (12.96 mM)

OT-551 HCl (intraperitoneally injected; rats; approximately 30 min prior to a 6 h exposure to 2700 lux white fluorescent light) significantly reduced the number of RPE cell nuclei in light-exposed eyes from water-treated animals. RPE damage index was significantly lower in the animals treated with any dose of OT-551 HCl compared to water-treated animals both in the inferior and superior hemispheres. Systemic administration of OT-551 HCl provides RPE cell protection against acute light damage.[1]