Purified Mouse Monoclonal Antibody (Mab)

DENR抗体;Density-regulated protein; DRP; Protein DRP1; Smooth muscle cell-associated protein 3; SMAP-3; DENR; DRP1

Mouse

This DENR antibody is generated from a mouse immunized with a recombinant protein of human DENR.

Human

IF~~1:25
FC~~1:25
IHC-P~~1:25
WB~~1:1000-1:2000

Predicted molecular weight: 22kD
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Monoclonal Antibody

1542CT106.51.79

IgG2b,κ

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Others

May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Involved in translation initiation; promotes recruitmnet of aminoacetyled initiator tRNA to P site of 40S ribosomes. Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits. Plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1.

O43583

Deyo J.E.,et al.DNA Cell Biol. 17:437-447(1998).
Nishimoto S.,et al.Submitted (MAY-1998) to the EMBL/GenBank/DDBJ databases.
Scherer S.E.,et al.Nature 440:346-351(2006).
Oh J.J.,et al.Nucleic Acids Res. 27:4008-4017(1999).
Reinert L.S.,et al.Cancer Res. 66:8994-9001(2006).