EPAC 5376753CAS号： 302826-61-5分子式： C15H8Cl2N2O3S分子量： 367.21描述储存/保存方法可溶性/溶解性靶点In vitro(体外研究)
| 产品描述 | |
| 描述 |
EPAC 5376753 is an allosteric inhibitor of EPAC1 with an IC50 of 4 µM in Swiss 3T3 cells.
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| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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| 基本信息 | |
| 可溶性/溶解性 |
DMSO:3.68 mg/mL (10.01 mM)
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| 生物活性 | |
| 靶点 |
Epac:4 µM
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| In vitro(体外研究) |
EPAC 5376753 decreases the conformational changes of EPAC necessary for its activation. EPAC 5376753 inhibits EPAC signaling in cells and EPAC-mediated migration in fibroblasts[1].
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