NRX-252262 is a potent enhancer of the interaction between β-Catenin, and its cognate E3 ligase, SCFβ-TrCP, induces mutant β-catenin degradation(EC50：3.8 nM)

98%

Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.

DMSO:8 mg/mL (14.67 mM)

β-Catenin-SCFβ-TrCP:3.8 nM (EC50)

NRX-252262 also induces S33E/S37A mutant β-catenin degradation at an even lower concentration of ~35?μM