Mouse anti-ETS1 Monoclonal Antibody(1601CT512.35.61)描述别名宿主特异性反应种属应用分子量类型克隆号同种型储存/保存方法研究领域背景说明细胞定位UniProt参考文献
| 概述 | |
| 描述 |
Purified Mouse Monoclonal Antibody (Mab)
|
| 别名 |
ETS1抗体;Protein C-ets-1; p54; ETS1; EWSR2
|
| 宿主 |
Mouse
|
| 特异性 |
This ETS1 antibody is generated from a mouse immunized with a recombinant protein of human ETS1.
|
| 反应种属 |
Human
|
| 应用 |
FC~~1:25
WB~~1:500 |
| 分子量 |
Predicted molecular weight: 50kD
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
| 性能 | |
| 类型 |
Monoclonal Antibody
|
| 克隆号 |
1601CT512.35.61
|
| 同种型 |
IgG2b,k
|
| 储存/保存方法 |
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
|
| 研究领域 |
Cancer;Cardiovascular
|
| 靶标 | |
| 背景说明 |
Transcription factor. Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts. May control the differentiation, survival and proliferation of lymphoid cells. May also regulate angiogenesis through regulation of expression of genes controlling endothelial cell migration and invasion.
|
| 细胞定位 |
Cytoplasm. Nucleus. Note=Delocalizes from nucleus to cytoplasm when coexpressed with isoform Ets-1 p27
|
| UniProt |
P14921
|
| 参考文献 | |
| 参考文献 |
Reddy E.S.P.,et al.Oncogene Res. 3:239-246(1988).
Watson D.K.,et al.Proc. Natl. Acad. Sci. U.S.A. 85:7862-7866(1988). Laitem C.,et al.Oncogene 28:2087-2099(2009). Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases. Bechtel S.,et al.BMC Genomics 8:399-399(2007). |
实验结果图
Anti-ETS1 Antibody at 1:500 dilution + MOLT-4 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 50 kDa Blocking/Dilution buffer: 5% NFDM/TBST.