NCT-501CAS号： 1802088-50-1分子式： C21H32N6O3 分子量： 416.52描述纯度储存/保存方法可溶性/溶解性靶点In vitro(体外研究)In vivo(体内研究)参考文献
| 产品描述 | |
| 描述 |
NCT-501 is a potent and selective inhibitor of Aldehyde Dehydrogenase 1A1 (ALDH1A1) with IC50 of 40 nM.
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| 纯度 |
99.56 %
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| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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| 基本信息 | |
| 可溶性/溶解性 |
体外:
DMSO 32mg/mLwarming(76.82mM) Ethanol 25mg/mL(60.02mM) Water <1mg> |
| 生物活性 | |
| 靶点 |
ALDH1A1
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| In vitro(体外研究) |
In Caco-2 cell line, NCT-501 exhibits excellent permeability.
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| In vivo(体内研究) |
In CD1 Mice, NCT-501 is well JPorbed and distributed but rapidly metabolized and/or excreted.
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| 参考文献 | |
| 参考文献 |
[1] Yang SM, et al. J Med Chem. 2015, 58(15), 5967-5978. |
分子结构图
