LY2606368CAS号： 1234015-52-1分子式： C18H19N7O2分子量： 365.38916描述纯度储存/保存方法别名可溶性/溶解性靶点In vivo(体内研究)
| 产品描述 | |
| 描述 |
LY2606368 is an inhibitor of checkpoint kinase 1 (chk1) with potential antineoplastic activity. |
| 纯度 |
>98%
|
| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
|
| 基本信息 | |
| 别名 |
LY 2606368; LY-2606368; Prexasertib
|
| 可溶性/溶解性 |
DMSO: ≥ 60 mg/mL
|
| 生物活性 | |
| 靶点 |
Checkpoint Kinase (Chk)
|
| In vivo(体内研究) |
LY2606368 (15 mg/kg, s.c.) significantly inhibits tumor growth in xenograft tumor models with less animal weight loss. LY2606368 (2 mg/kg, s.c.) and BMN673 combination has synergistic anticancer effect in gastric cancer PDX model, and the effect is higher than that of one drug alone.
|
分子结构图
